Weight loss

Weight loss medication

Trustpilot stars
4.4/5 on Trustpilot
8,471 reviews

Clinically proven to help you lose weight.

Weight loss medication thats proven to help you lose more weight that dieting alone.

Why customers choose us
Money
180 days Money Back Promise
Medical
On hand support and prescribing clinicians
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Achieve lasting results beyond your medication
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From £135
£229 per month thereafter
Am I eligible?
Refills
Cancel-any-time plans
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The No.1 medicated programme

We are the UK's leading medicated weight loss programme, with over 10,000 UK members.

Trustpilot stars
TrustScore 4.4/5
8,471 reviews

I have found the plan to be excellent so far. My appetite was significantly suppressed from week one, I have lost 1st 6lbs in 7 weeks.

Trustpilot stars
Suzanne W. Trustpilot

From first use appetite and interest in food generally has changed completely. For the first time in years I feel in control of food.

Trustpilot stars
Jo P. Trustpilot

Talking to a coach is a game changer, it gave me confidence to start my weight loss journey.

Trustpilot stars
Christine. Trustpilot

Decided to try it as I have tried and failed to lose utilising ever diet and eating plan known to man! I have lost 12lbs so far.

Trustpilot stars
Linda. Trustpilot

I started my treatment 4 weeks ago and up to now I’ve lost a stone. I have found all the instructions easy to follow.

Trustpilot stars
Anne K. Trustpilot

I have started eating better and walking for at least an hour every day. I am only on my 3rd injection and I have already lost half a stone.

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Peter. Trustpilot

Great support from the start and great losses, I have seen so far I have lost 24 pound in my first month.

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Stuart L. Trustpilot

Our programme

How much weight can I lose?
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With MANUAL, we prepare you to get the most out of your medication while setting you up for long term success. It’s why people who engage with our MANUAL plan lose 20% more weight by month 6.

Are there any side effects?
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Some people experience side effects with medication, however these tend to be mild and subside as your body adjusts to the medication. The most common side effects are nausea and diarrhoea.

Why should I use MANUAL?
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With MANUAL, you get access to a holistic weight loss plan beyond just medication. Enjoy unlimited access to:

  • Prescribing clinicians to answer any questions about your medication
  • Your own health coach to help you build long-lasting habits and maintain progress
  • An online toolkit of content and help tracking your weight

Our tailored weight loss package is why 84% of our customers say we are the most effective plan they have tried.

How to get started

Assessment

Free online assessment

Find out if you’re eligible for medication in just one minute with our online assessment.

Recommendation

Get your recommendation

Our experts will recommend the right weight loss treatment plan for you.

Delivery

Free discreet delivery

Get your treatment delivered to your front door, discreetly and for free.

20% more effective than medication alone

WL chart

With MANUAL, we prepare you to get the most out of your medication while setting you up for long term success. Its why people who engage with MANUAL lose 20% more weight by month 6.

Citations
Citations

From a internal study of 1,547 participants

Why the MANUAL plan?

A powerful, science-backed solution to help you look and feel better.

Wevoy and Ozempic Pen

Weight loss medication

Breakthrough medication that is clinically proven to be more effective than dieting alone.

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Science-backed medication
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Kickstart your weight loss
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Licensed by the MRHA
Wevoy and Ozempic Pen

Dedicated coaching & support

Stay motivated, engaged and accountable with the help of our expert weight loss coaches.

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On-demand medical support from clinicians
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1:1 personal coaching service
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Rewire your eating habits for good

Thousands of people in the UK trust MANUAL

Camelia lost 16kg in 2 months

“This program has completely changed my life, because I am a diabetic and had previous difficulty in losing weight. Now, I eat much healthier, drinking more water, exercising and being optimistic. My sleep and the level of energy has improved a lot, I don’t crave junk food, fizzy drinks, sweets, I don’t make anymore late night visits to the kitchen and so many other positive changes.”

Day 1
Camelia before
Camelia after
Month 2

Julia lost 11kgs in 4 months

"Whilst the medication undoubtedly helps with the weight loss, for me, the biggest support is the counselling. My coach, Maria is really supportive. To have someone that gives you ideas on what you can change and then you hold yourself accountable which is what I think is needed for long term success."

Day 1
Julia before
Julia after
Month 4

Emma lost 9.5kg in 7 months

“I had tried most diets with little success and I was desperate to lose weight to enable me to do my skydive! My coach and medication has given me new confidence to continue my weight loss journey! We all have bad days but your coach completely understands and doesn’t make you feel bad about it”

Day 1
Emma before
Emma after
Month 7

Karen lost 9kg in 3 months

“My appetite has significantly reduced which has helped me in stopping my habit of snacking. I have also noticed that my portion size has decreased. All adding to the results.”

Day 1
Karen before
Karen after
Month 3

Jo lost 53lbs in 4 months 

“Medication has changed my life, I can’t believe how much weight I have lost in such little time. I feel so much better in myself physically and mentally. MANUAL have been a great support during this time, regularly checking in.”

Day 1
Jo before
Jo after
Month 4

Emily lost 16.4 kg in 4 months. 

“I've spent years yo-yo dieting, following the latest fads and getting nowhere—only growing larger. After yet another failed attempt at a different diet, I decided to try MANUAL. From assessment to delivery, it was lightning-fast! The 'food noise' disappeared, and I started seeing results on the scales. It's the easiest plan I've ever been on. The medication holds your hand—it's like willpower in a bottle—and my nutritionist/coach supports and guides me. I'm confident I'll reach my goal.”

Day 1
Emily before
Emily after
Month 4

Ella lost 16kg in 11 weeks

I’ve always struggled with my weight, but after a traumatic birth in 2021 it quickly ballooned out of control. I could barely walk for 5 minutes and simple things like picking up my toddler and showering became monumental tasks. My confidence was non-existent and I found myself not leaving the house unless I absolutely had to. Being so overweight came with a host of concerning health issues. Eleven weeks into my plan and I can truly say I believe the programme will save my life. The change is absolutely incredible. Not only have I lost 36lbs, it’s been over a month since I had to rely on a walking aid, I’m no longer pre-diabetic, I’ve joined an outdoor swimming group and I’m in the best place mentally that I have been in years!

Day 1
Ella before
Ella after
Month 3

Vinda lost 15kg in 4 months

“I knew I needed to make a change to my health and wellbeing. My relationship with food was awful. It was an emotional crutch. This has now completely transformed! I am drawn to healthier foods and my whole lifestyle has changed. I have lost 15kgs in 4 months and I haven't looked/felt this confident in 10 years! I'm wearing prettier clothes and I feel sexy! I can't recommend it enough!”

Day 1
Vinda before
Vinda after
Month 4
Trustpilot stars
TrustScore 4.4/5
8,471 reviews

Your weight loss journey

0 to 3 months

Start to feel the effects

It can take up to 8-9 weeks to feel the full effects of your medication. Your clinician will adjust your treatment as you go to maximise your results.

3 to 6 months

Lose 5-10% bodyweight

By continuing to move forward with our programme, you’ll lose at least 10% of your body weight by the end of month 6.

6 to 12+ months

Build habits for life

You and your coach will chart your course to lasting weight loss, with a plan for sticking to your new healthy habits.

Our results speak for themselves.

84%

of members say this is the most effective program they have tried

92%

of members are confident they will keep the weight off for good

97%

of members felt their overall health had improved

¹Taken from a customer care survey from 300 patients over 6 months of treatment. Based on a  survey of 215 active patients, February 2023

Backed by experts in science and behavioural change

David Huang

David Huang

Deputy Medical Director

Trained at King’s College London, David has many years experience as a GP working in endocrinology and women’s health. He is passionate about supporting patient’s metabolic health and driving positive outcomes beyond weight loss alone.

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Madeline Hawk

Madeline Hawk

Behaviour Change Expert

Trained as a Psychologist and Registered Dietitian, Madeleine bridges the gap between devising the right diet for you and overcoming the psychological hurdles to consistently following it.

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Phoebe Fox

Phoebe Fox

Clinician

Phoebe its an Independent Prescriber with specialist training in obesity care. She works with patients to evaluate the right treatment options for them to maximise their results.

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Everything you need to know

How much weight will I lose?
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Everyone is different - take our questionnaire and we’ll calculate your weight loss potential.

How long is the programme?
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We recommend following our programme for at least six months to see significant results. However, the programme is set up as a monthly subscription so you can take it one month at a time.

Do the medications have side effects?
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As with all medication, you may experience some side effects, however these tend to be mild and can be reduced with tips from our clinicians. Please refer to the patient information leaflet for more information.

What happens when I stop the medication?
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Medication alone can help you lose weight, but it will not help you keep it off. That is why we pair medication with coaching, to help you make long term changes to your habits that will help you keep the weight off after you stop the medication.

How does the moneyback promise work?
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We are confident that you will see results on our program. That is why, if you do not lose at least 10% of your body weight in six months, we will refund you the difference. For example if you lose 8% of your body weight we will refund you 20% of the program cost. Terms apply.