Weight loss

Weight loss injections

Trustpilot stars
4.4/5 on Trustpilot
10.2k reviews

Clinically proven to help you lose up to 20% of your body weight

Why customers choose us
Money
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Medical
On hand support and prescribing clinicians
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Achieve lasting results beyond your medication
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From £135
£229 per month thereafter
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The right weight loss medication for you

Take our quiz and get recommended a weight loss medication that works for you.

Weight loss

GIP/GLP-1 Injection

Shield
Most effective for weight loss
Proven results
20% body weight lost
Weight loss

GLP-1 Injection

Shield
Lighter side effect profile
Proven results
15% body weight lost
Weight loss

Orlistat

Shield
Over-the-counter
Proven results
5% body weight lost

How to get started

Assessment

Free online quiz

Find out if you’re eligible for medication in just one minute with our online quiz.

Weight loss

Get your recommendation

Our experts will recommend the right weight loss injection plan for you.

Delivery

Free discreet delivery

Get your treatment delivered to your front door, discreetly and for free.

Why the MANUAL plan?

A powerful, science-backed solution to help you look and feel better.

Wevoy and Ozempic Pen

Weight loss injections

Clinically proven to help you lose weight, our medication is designed to help you beat hunger.

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Science-backed prescription medication
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Reduces hunger and cravings
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MHRA licensed medication
Wevoy and Ozempic Pen

Dedicated coaching & support

Stay motivated, engaged and accountable with the help of our expert weight loss coaches.

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On-demand medical support from clinicians
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1:1 personal coaching service
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Hit your weight loss goals beyond medication
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The No.1 medicated programme

We are the UK's leading medicated weight loss programme, with over 10,000 UK members.

Trustpilot stars
TrustScore 4.4/5
10.2k reviews

I have found the plan to be excellent so far. My appetite was significantly suppressed from week one, I have lost 1st 6lbs in 7 weeks.

Trustpilot stars
Suzanne W. Trustpilot

From first use appetite and interest in food generally has changed completely. For the first time in years I feel in control of food.

Trustpilot stars
Jo P. Trustpilot

Talking to a coach is a game changer, it gave me confidence to start my weight loss journey.

Trustpilot stars
Christine. Trustpilot

Decided to try it as I have tried and failed to lose utilising ever diet and eating plan known to man! I have lost 12lbs so far.

Trustpilot stars
Linda. Trustpilot

I started my treatment 4 weeks ago and up to now I’ve lost a stone. I have found all the instructions easy to follow.

Trustpilot stars
Anne K. Trustpilot

I have started eating better and walking for at least an hour every day. I am only on my 3rd injection and I have already lost half a stone.

Trustpilot stars
Peter. Trustpilot

Great support from the start and great losses, I have seen so far I have lost 24 pound in my first month.

Trustpilot stars
Stuart L. Trustpilot

Thousands of people in the UK trust MANUAL

Camelia lost 16kg in 2 months

“This program has completely changed my life, because I am a diabetic and had previous difficulty in losing weight. Now, I eat much healthier, drinking more water, exercising and being optimistic. My sleep and the level of energy has improved a lot, I don’t crave junk food, fizzy drinks, sweets, I don’t make anymore late night visits to the kitchen and so many other positive changes.”

Day 1
Camelia before
Camelia after
Month 2

Julia lost 11kgs in 4 months

"Whilst the medication undoubtedly helps with the weight loss, for me, the biggest support is the counselling. My coach, Maria is really supportive. To have someone that gives you ideas on what you can change and then you hold yourself accountable which is what I think is needed for long term success."

Day 1
Julia before
Julia after
Month 4

Emma lost 9.5kg in 7 months

“I had tried most diets with little success and I was desperate to lose weight to enable me to do my skydive! My coach and medication has given me new confidence to continue my weight loss journey! We all have bad days but your coach completely understands and doesn’t make you feel bad about it”

Day 1
Emma before
Emma after
Month 7

Karen lost 9kg in 3 months

“My appetite has significantly reduced which has helped me in stopping my habit of snacking. I have also noticed that my portion size has decreased. All adding to the results.”

Day 1
Karen before
Karen after
Month 3

Jo lost 53lbs in 4 months 

“Medication has changed my life, I can’t believe how much weight I have lost in such little time. I feel so much better in myself physically and mentally. MANUAL have been a great support during this time, regularly checking in.”

Day 1
Jo before
Jo after
Month 4

Emily lost 16.4 kg in 4 months. 

“I've spent years yo-yo dieting, following the latest fads and getting nowhere—only growing larger. After yet another failed attempt at a different diet, I decided to try MANUAL. From assessment to delivery, it was lightning-fast! The 'food noise' disappeared, and I started seeing results on the scales. It's the easiest plan I've ever been on. The medication holds your hand—it's like willpower in a bottle—and my nutritionist/coach supports and guides me. I'm confident I'll reach my goal.”

Day 1
Emily before
Emily after
Month 4

Ella lost 16kg in 11 weeks

I’ve always struggled with my weight, but after a traumatic birth in 2021 it quickly ballooned out of control. I could barely walk for 5 minutes and simple things like picking up my toddler and showering became monumental tasks. My confidence was non-existent and I found myself not leaving the house unless I absolutely had to. Being so overweight came with a host of concerning health issues. Eleven weeks into my plan and I can truly say I believe the programme will save my life. The change is absolutely incredible. Not only have I lost 36lbs, it’s been over a month since I had to rely on a walking aid, I’m no longer pre-diabetic, I’ve joined an outdoor swimming group and I’m in the best place mentally that I have been in years!

Day 1
Ella before
Ella after
Month 3

Vinda lost 15kg in 4 months

“I knew I needed to make a change to my health and wellbeing. My relationship with food was awful. It was an emotional crutch. This has now completely transformed! I am drawn to healthier foods and my whole lifestyle has changed. I have lost 15kgs in 4 months and I haven't looked/felt this confident in 10 years! I'm wearing prettier clothes and I feel sexy! I can't recommend it enough!”

Day 1
Vinda before
Vinda after
Month 4
Trustpilot stars
TrustScore 4.4/5
10.2k reviews

20% more effective than medication alone

WL chart

With MANUAL, we prepare you to get the most out of your medication while setting you up for long term success. Its why people who engage with MANUAL lose 20% more weight by month 6.

Citations
Citations

From a internal study of 1,547 participants

How it works

1

Take our assessment

Answer a few questions to help us understand your symptoms.

2

Receive your treatments

Next day delivery, discretely packaged

3

Get ongoing support

Speak to your clinician at any point

Phone
Everything happens on your phone
Delivery
Free next day delivery (medication)
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